Systemic sclerosis

Scleroderma (systemic sclerosis, SSc) is a chronic, progressive dermatosis characterized by board-like hardening and immobility of the affected skin, with visceral involvement, especially of the lungs, oesophagus, kidneys and heart. It may be accompanied by calcinosis, Raynaud's phenomenon and telangiectasis (limited cutaneous systemic sclerosis, formerly known as CREST syndrome). It includes acrosclerosis and sclerodactyly.