Systemic Sclerosis

Scleroderma (systemic sclerosis, SSc) is a chronic, progressive dermatosis characterized by boardlike hardening and immobility of the affected skin, with visceral involvement, especially of lungs, esophagus, kidneys and heart. It may be accompanied by calcinosis, Raynaud's phenomenon, and telangiectasis (limited cutaneous systemic sclerosis, formerly known as CREST syndrome). It includes acrosclerosis and sclerodactyly.