Plaice

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Code: f254
Latin name: Pleuronectes platessa
Source material: Fish muscle
Family: Pleuronectidae
Specific IgE antibodies are reported in several studies.

Allergen Exposure

Cooked, fried or otherwise prepared in various fish dishes.

Potential Cross-Reactivity

Species within groups of fish, like Gadiformes (examples: codfish and hake) and Scombroid fish (examples: mackerel and tuna) seem to share allergenic components. The overlap of allergen specificity between the groups seems to be moderate or even small.

Clinical Experience

Specific IgE antibodies have been measured in atopic dermatitis patients (1, 2), and in food-allergic children (3) using Pharmacia CAP System. The clinical sensitivity and specificity of f254 Plaice was reported to be 86% and 94% respectively (4).
 
Review
A salt water flat fish with white flesh, Plaice is commercially fished on both sides of the Atlantic. Its length is rarely over 60 cm, although before it was heavily fished, it could be over one meter. Species within groups of fish, like Gadiformes (examples: codfish and hake) and Scombroid fishes (examples: mackerel and tuna) seem to share allergenic components. The overlap of allergen specificity between the groups seems to be moderate or even small. Specific IgE antibodies have been measured in atopic dermatitis patients (1, 2), and in food-allergic children (3) using Pharmacia CAP System. The clinical sensitivity and specificity of f254 Plaice was reported to be 86% and 94% respectively (4).

References

  1. Konatsu H, Miyagawa K, Ikezawa Z. Study of clinical efficacy of Pharmacia CAP System new allergens in patients with atopic dermatitis. Japanese Soc Allergol 1992.
  2. Lindqvist A, Ikezawa Z, Tanaka A, Yman L. Seafood specific IgE in atopic dermatitis. Ann Allergy1993;70:58.
  3. Matsumaru S, Artia M et al. Clinical evaluation of Pharmacia CAP System new allergens for fish, vegetables, fruits and grains. Jap Soc Ped Allergol 1992.
  4. Hansen TK, Abrahamsen L, Bindslev-Jensen C, Poulsen LK. Results of the CAP System and Immunoblotting in clinically fish allergic adults. Allergologie 1995;18:407.

As in all diagnostic testing, the diagnosis is made by the physican based on both test results and the patient history.