Swordfish

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Code: f312
Latin name: Xiphias gladius
Source material: Fish muscle
Family: Xiphidae
A patient with clinical sensitivity to swordfish had IgE antibodies to a 25 kD protein but to no other protein from 10 fish species tested.

Potential Cross-Reactivity

Species within groups of fish, like Gadiformes (examples: codfish and hake) and Scombroid fishes (examples: mackerel and tuna) seem to share allergenic components. The overlap of allergen specificity between the groups seems to be moderate or even small.
 
Review
Swordfish is an enormous mackerel-like fish representing the only member of the family Xiphidae. It feeds on schools of fishes. The prolongation of the forepart of the skull into a horizontally flattened "sword" is a formidable weapon which can pierce wooden boats. An Atlantic and Mediterranean fish, it is seen only occasionally in the Pacific. A patient with clinical sensitivity to swordfish had IgE antibodies to a 25 kD protein but to no other protein from 10 fish species tested. The allergen may be specific for the family Xiphidae (1).

References

  1. Kelso, JM; Jones, RT; Yunginger, JW. Mono specific allergy to swordfish. Ann Allergy Asthma Immunol; 1996; 77: 227-228.

As in all diagnostic testing, the diagnosis is made by the physican based on both test results and the patient history.