Methohexital is a barbiturate derivative used for brief surgical procedures.
Reported incidence ranges from 1/7000 to 0/23000.
0.2% in dentistry.
No deaths have been reported.
Essentially cutaneous, mucosal (pruritus, urticaria, rash, edema) and cardiovascular.
Respiratory (bronchospasm) and digestive symptoms are unusual.
Symptoms are usually delayed (a few minutes after injection).
Non specific histamine-release.