Etomidate


Short-acting general anesthetic.
 
Incidence
Exceedingly rare.
 
Clinical manifestations
Essentially cutaneous and gastrointestinal.
 
Few cardiovascular and respiratory effects.
 
Diagnostic methods
No in vivo or in vitro diagnostic method currently available.
 
Mechanisms
Etomidate is a poor histamine releaser.
 
Management
Avoidance.
 

References

  1. Fazackerley E.J, Martin A.J, Tolhurst-Cleaver C.L, Watkins J, "Anaphylactoid reaction following the use of etomidate", Anaesthesia, 1988 ; 43 (1): 953-4.
  2. Bricker S.R, "Angioneurotic edema following etomidate/lignocaine", Anaesthesia, 1987 ; 42 (3): 323-4.
  3. Watkins J, "Etomidate, an "immunologically safe" anaesthetic agent", Anaesthesia., 1983 ; 38 (S): 34-8

As in all diagnostic testing, the diagnosis is made by the physican based on both test results and the patient history.