Fluconazole is a triazole antifungal agent used in the treatment of infections of the nails, skin, oral and vaginal mucosa; systemic candidiasis, cryptococcal meningitis and as prophylaxis for cryptococcal infections in HIV patients.
Probably very low.
Rashes, maculopapular eruptions, fixed drug eruptions, angioedema, toxic epidermal necrolysis, Stevens-Johnson’s syndrome.
One case with positive skin-prick tests 1/10.
Cross-reactivity with other azole derivatives is likely.
Desensitization (orally): 0.2 mg to 400 mg in 15 days.