Widely used antiseptics: mercurochrome, thiomersal, phenylmercuric acetate.
Systemic reactions are uncommon. Delayed cutaneous reactions are common.
General: anaphylactic shock.
Cutaneous: acute urticaria, facial edema, contact dermatitis.
E.N.T.: laryngeal edema.
- Prick and intradermal tests with mercury chloride, mercury nitrate, phenylmercury acetate, mercurochrome, thiomersal, thiosalicylic acid. Results may be positive following an acute reaction.
- Patch-test may be positive in patients with contact dermatitis (thiomersal).
IgE-mediated hypersensitivity may be implicated in immediate reactions. One positive Prausnitz-Küstner test has been reported.
Cell-mediated hypersensitivity in patients with contact dermatitis.
In addition to products for external use, some vaccines also contain mercury antiseptics (antituberculosis, antihepatitis B).