Povidone iodine


Povidone iodine is widely used as an antiseptic.
 
Incidence
Rare.
 
Clinical manifestations
Cutaneous: contact eczema.
 
Diagnostic methods
Cutaneous testing.
 
Patch-tests:
  • Positive with Betadine solution, Betadine ointment, Betadine scrub 2% in water, povidone iodine 10% in pet.
     
  • Negative with potassium iodide 5, 10, 15, 20% in pet.
     
  • Negative with iodine tincture (open test).
Mechanisms
Type IV hypersensitivity.
 
Management
Avoidance.

References

  1. van Ketel W.G, van der Berg W.H.H.W, "Sensitization to povidone-iodine", Dermatol. Clin., 1990; 8 (1): 107-9 
  2. Ancona A, Suarez de la Torre R, Macotela E, "Allergic contact dermatitis from povidone-iodine", Contact Dermatitis, 1985; 13: 66-8  
     

As in all diagnostic testing, the diagnosis is made by the physican based on both test results and the patient history.