Vitamin B6


Pyridoxine, pyridoxal and pyridoxamine are 3 biologically similar interchangeable compounds referred to as vitamin B6. Pyridoxine is widely used in the preparation of medications and cosmetics (hair lotion).
 
Incidence
Contact dermatitis is infrequent.
 
Photoallergy is exceptional.
 
Clinical manifestations
Contact dermatitis, photosensitive dermatitis.
 
Diagnostic methods
Cutaneous testing
 
Patch -tests and photopatch-tests: pyridoxine hydrochloride
(1% pet).
 
Mechanisms
Delayed hypersensitivity.
 
Photoallergy.
 
Management
Avoidance.

References

  1. Tanaka M, Niizeki H, Shimizu S, Miyakawa S, "Photoallergic drug eruption due to pyridoxine hydrochloride", J. Dermatol., 1996; 23 (10): 708-9 
  2. Camarasa J.G, Serra-Baldrich E, Lluch M, "Contact allergy to vitamin B6", Contact. Dermatitis, 1990; 23 (2): 115 
     

As in all diagnostic testing, the diagnosis is made by the physican based on both test results and the patient history.