Incidence: low since the product is now only handled in a closed environment in order to prevent occupational exposures.
Diazomethane is used as a methylating agent. It will cause symptoms when present as an airborne contaminant (level >0.1mg/m3).
No pre-disposing factors.
Through loss of nitrogen, diazomethane forms a carbene which possesses a highly electrophilic double free radical.
Severe asthma (in all exposed subjects). Cases of airways cancer have also been reported
The clinical symptoms appearing in the work place are the only means of diagnosis.