Asthma caused by organo-phosphorous insecticides


Occupations
  • Farmer
  • Gardener
  • Horticulturist
  • Landscape gardener
  • Service Personnel
  • Wine grower
Agents
Chlorothion, Diazinon, Dichlorvos, Malathion, Parathion.
 
Incidence
Incidence: rare.
 
Mechanism: inhibition of cholinesterases.
 
Specific treatment with Contrathion RP.
 
Conditions
Use of insecticides in confined spaces or without adequate precaution, most commonly during disinfection.
 
Symptoms
Acute paroxysms of dyspnoea may develop into pulmonary oedema and can continue after work has ceased.
 
Diagnostic methods
No skin or bronchial provocation tests available.
 
Investigation of work activities and measurement of plasma and total cholinesterase levels are the only diagnostic tools available.

References

  1. Ann. Allergy 1961, 19:397

As in all diagnostic testing, the diagnosis is made by the physican based on both test results and the patient history.