Asthma caused by casein


Occupations
  • Food industry
  • Tanner
Agents
Casein
 
Incidence
Rare, IgE-dependent mechanism. Approximately 50% of subjects are atopic.
 
Conditions
Sensitisation usually occurs via the digestive tract.
 
Inhalation of casein is responsible for occupational asthma.
 
Symptoms
Rhinitis and asthma develop after several years of exposure to the risk.
 
Diagnostic methods
Skin tests: skin prick tests using commercially available allergens: immunological dosage using RAST/CAP.
 
Bronchial provocation test (in hospital) is conducted using a solution of 10-50 mg/ml.

References

  1. J. Allergy Clin. Immunol. 1994,93,4:799
    Allergy 1990,45:306

As in all diagnostic testing, the diagnosis is made by the physican based on both test results and the patient history.