Why do we sometimes see very small spots?

Sometimes we see small white circles positioned for a normal sized spot. We know how to fix this, but why is it a small circle?
Concerning the feature (white ring) that cannot find the spot correctly: One explanation could be; there is a darker area in the middle of the spot which is slightly bigger than for the other two spots in the triplicate. The algorithm always tries to find the edges when placing the features (white rings) in this case, the derivate can be bigger between areas inside the spot than between the spot edge and the background. We need the original tiff-image to verify this. Meanwhile you have to be observant and move features manually or use the keyboard combination CTRL + A (when the image view is selected), which will run the algorithm once again.
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As in all diagnostic testing, the diagnosis is made by the physican based on both test results and the patient history.