What are the differences between the old (103) and the updated (112) ISAC chip?

What are the differences between the old (103) and the updated (112) ISAC chip?
The binding chemistry has been improved on the new chip, which now also includes 112 components instead of 103 plus the calibration concept has been updated The components selection has also been updated and all the information about which components are replaced, updated or added and the rationale behind this, is documented in “New components and the rationale behind” at DiaNet --> Molecular Allergology --> ImmunoCAP ISAC --> Marketing material.
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As in all diagnostic testing, the diagnosis is made by the physican based on both test results and the patient history.