How come that a patient with a negative Phadiatop could have a positive e.g. Nut mix?
Phadiatop only contains inhalant allergens and does not contain pure food allergens. If the patient has an isolated nut allergy and is sensitized only to allergens contained in the food/nut, e.g. storage proteins, the patient will be negative on Phadiatop. The majority of food allergic patients are co-sensitized to inhalant allergens and will thus be identified with Phadiatop as atopic anyway, but some patients do have a “pure” food allergen sensitization and will only be identified when testing with the appropriate food allergens. If true nut allergy is suspected, the patient could get very severe reactions such as anaphylaxis and the specific nut should always be the test of choice.
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