Why using Phadiatop as a “screening test” instead of Total IgE?

Why is it better to use Phadiatop as a “screening test” instead of Total IgE when atopic allergy is suspected?

Only around 50 % of patients with respiratory allergies have increased total IgE (>100 kU/l), which in fact means that 50 % with normal total IgE will not be identified by total IgE testing.

The total IgE level is the sum of all IgE in the blood, which can be increased due to other reasons than allergy. Instead Phadiatop is recommended with its superior performance, which only measures allergen-specific IgE antibodies to common allergens and not the total amount where irrelevant IgE could be included.

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As in all diagnostic testing, the diagnosis is made by the physican based on both test results and the patient history.