Why should omega-5 gliadin (f416) be used together with Gliadin (f98)?
While Gliadin (f98) has a high sensitivity for detecting sensitization to gliadins, the specificity of w-5 gliadin (f416) is higher. Available data – published and preliminary – indicate that by combined testing for gliadin- and w-5 gliadin-specific antibodies most patients with immediate type wheat allergy, and WDEIA – see Hofmann et al. 2013., can be identified.
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The majority of patients with wheat symptoms are sensitized to both gliadin and omega-5 gliadin.
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